| abstract |
A method and compositions are disclosed for, among other things, in an anima l, (i) improving the elasticity or reducing wrinkles of the skin, treating (ii) diabetes or treating or preventing (iii) adverse sequelae of diabetes, (iv) kidney damage, (v) damage to blood vasculature, (vi) hypertension, (vii) retinophathy, (viii) damage to lens proteins, (ix) cataracts, (x) peripheral neurophaty, or (xi) osteoarthritis. |