http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2399067-A1

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filingDate 2001-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fccbe236002ee18a71a7e2d6da3a079b
publicationDate 2001-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2399067-A1
titleOfInvention Method for diagnosing efficacy of xenotypic antibody therapy
abstract The invention provides methods for diagnosing the efficacy of a patient to xenotypic antibody therapy which include (1) measuring the level of an antibody produced by a patient that specifically binds to a xenotypic antibo dy after administration of the xenotypic antibody to the patient; (2) measuring the level of an anti-idiotype antibody produced by a patient that specifical ly binds to a xenotypic antibody after administration of the xenotypic antibody to the patient; (3) measuring the level of an antibody produced by a patient that specifically binds to a target antigen of a xenotypic antibody after administration of a xenotypic antibody to the patient; and (4) measuring the level of a T cell response produced by a patient to a target antigen of the xenotypic antibody after administration of a xenotypic antibody to the patient. In the methods of the invention, an increase in the level of antibo dy or T cell response produced by the patient after the administration of the xenotypic antibody relative to the level antibody or T cell response produce d by the patient prior to the administration of the xenotypic antibody is indicative of a favorable diagnosis of efficacy.
priorityDate 2000-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 29.