| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2baf849d216e689ecc40ccc931a7a7bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9cb217f83556ce2a418344c2d485415 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-12 |
| filingDate |
2001-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b49ce0bf464ed9596666111f66b82e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94a9cb0cc53bd2a2fed32fb1e849f6b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adb5c8d1f4aeaa0c4e08fc5e48685ab3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42716f4eacb00571d1c7db0f43633f81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a545ec9a945f25f7996bb80385bede6 |
| publicationDate |
2010-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2398113-C |
| titleOfInvention |
Process for preparing quinolylacrylonitrile and intermediates therefor |
| abstract |
3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]prop-2-enenitrile represented by (3) is prepared by reacting 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde represented by (1) with acetonitrile in the presence of a base and then adding a dehydrating to the reaction mixture to conduct dehydration. Under ordinary conditions, novel 3-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-3-hydroxypropionitrile represented by (2) is formed as an intermediate in the above reaction. Incidentally, when the above reaction is conducted in an organic solvent, 3-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-prop-2-enenitrile is directly formed. (see formula 1) (see formula 2) (see formula 3) |
| priorityDate |
2000-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |