| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9217fdade858bfb104397009736dfb02 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-812 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-734
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2000-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0d5f46f5c4d9dfc3e912c787cd0ae36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6db3793b5a3094a6d1aa7dd2905d071e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6de6a25e9e74383e3f277aaaca92b00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa3b618ac3a204c9adca306eeff16f85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71acd51e3f47dbb9c22b23709de4dfbb |
| publicationDate |
2001-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2396744-A1 |
| titleOfInvention |
Synthetic lipid-a analogs and uses thereof |
| abstract |
New synthetic Lipid-A analogs based on monosaccharide (1) and disaccharide ( 2) derivatives were designed and prepared in the present invention. Both structures (1) and (2) incorporate novel lipid structures (3) and (4) that a re not found in nature. Also, novel disaccharide Lipid-A structures (2) that incorporate novel contingents of uniform lipids and where R1, R4 and R5 are the same substitution group of structure (III) were synthesized. Liposome formulations containing totally synthetic components such as synthetic Lipid -A and synthetic lipopeptide derived from tumor-associated MUC1 mucin are described along with their therapeutic utility. Comparative test results of immunostimulating properties and toxicity of Lipid-A analogs (1) and (2) are included. |
| priorityDate |
1999-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |