abstract |
Novel heterocyclic dihydropyrimidine compounds useful as inhibitors of potassium channel function (especially inhibitors of the K v1 subfamily of voltage gated K+ channels, especially inhibitors K v1.5 which has been linked to the ultra-rapidly activating delayed rectifier K+ current I Kur), methods of using such compounds in the prevention and treatment of arrhythmia and I Kur-associated conditions, and pharmaceutical compositions containing such compounds. |