| abstract |
This invention provides novel compounds and methods and compositions using them in the treatment of central nervous system disorders, including depression and anxiety, the compounds having the formula (I) wherein Ar is an aryl, arylalkyl or a heteroaryl group; R1 and R2 are independently selected from hydrogen, alkyl of 1 to 12 carbon atoms which may be substituted or cycloalkyl of 3 to 10 carbon atoms which may be substituted; R3 is H, alkyl which may be substituted, cyclic alkyl which may be substituted, halogen, alkoxy, haloalkyl, OH, nitro, amino, CN, carboxy, alkoxycarbonyl, alkylcarbonyl, aminocarbonyl and alkylaminocarbonyl; or a pharmaceutically acceptable salt thereof. |