| abstract |
The invention relates to novel compounds of formula (I): in which R represents a hydrogen atom or an alkyl group eventually substituted or alkenyl; R1 to R8, identical or different, each represent an atom of hydrogen or an optionally substituted alkyl group, hydroxy, acyloxy, amino optionally substituted, carboxy, optionally substituted alkoxy or alkenyloxy, or one of the groups R1 to R8 forms with another group R1 to R8 contiguous with alkylenedioxy group; X represents an oxygen atom or a group in which R16 represents a hydrogen atom or an alkyl or aryl group or arylalkyl; and R9 represents a hydrogen atom, an aryl group or heteroaryl or a saturated or unsaturated, optionally substituted alkyl group. The invention aims also the isomers of the compounds of formula (I), as well as their salts of addition to a acid or a pharmaceutically acceptable base. The compounds according to the invention are useful as drugs for the treatment of cancers. |