Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2817954cd008bcd609a4c4eb49050be |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2000-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b778ed81e89dc7a3a67cc779a17d7e5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75508132e5381cea0cedebf49af51618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a35187346da443933af1fbe5a14c4d76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8469506ee5c271a84e9bbda8900b40d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43f267aec742722c7983fc12ab5543d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a14101d6f17f92e4ae054d3dabea9961 |
publicationDate |
2001-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2389676-A1 |
titleOfInvention |
Substance capable of controlling the inclusion of exon 10 of the tau gene, and its therapeutic use against tauopathies |
abstract |
The present inventions relates to substances which are capable of controlling the inclusion of exon (10) of the tau gene. The substances can reverse "wrong" tau splicing pattern and. Since "wrong" tau splicing patterns are associated with tauopathies that cause dementia, the substances can be used as therapeutic agents. The invention also provides a method for testing substances that control tau exon (10) inclusion. The method is suitable for a high throughput screening. Additional products which are useful for changing tau exon (10) expression or for performing the test method are described as well. |
priorityDate |
1999-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |