http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2389626-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cea72e2de3c0219165474e54e9842d16 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M37-0092 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B18-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M35-00 |
filingDate | 2000-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a564443a5ac467319d836de695fcb055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01a7837858ad3029b7f5dbfb1b478f9e |
publicationDate | 2001-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2389626-A1 |
titleOfInvention | Method of forming micropores in skin |
abstract | A method of forming pores (600) in the stratum corneum (210) includes applying an aqueous material (123) to a surface area of the stratum corneum followed by the application of sonic and/or ultrasonic radiation (112) to said aqueous material wherein said sonic and/or ultrasonic radiation has a frequency in the range of 10KHz and 5 MHz and is applied at an intensity, for a period of time and at a distance from said surface area of the stratum corneum effective to generate cavitation bubbles (500) on said surface area of the stratum corneum, wherein said cavitation bubbles collapse and transfer their energy into the stratum corneum causing the formation of pores. Large size molecules ( > 500Da) dissolved in the aqueous material can transfer through these pores and across the stratum corneum and reach the blood vessels at flow rates suitable for therapeutic applications. |
priorityDate | 1999-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.