| abstract |
Compounds represented by general formula (I), salts thereof or prodrugs of the same which have an excellent effect of inhibiting binding of somatostatin receptor and, therefore, are efficacious in preventing and treating diseases in which somatostatin participates, etc., wherein X and X' are the same or different and each represents hydrogen, fluorine, etc., provided that at least one of X and X' represents fluorine, chlorine, etc.; R1 and R2 represents each hydrogen or optionally substituted C1-6 alkyl, or R1 and R2 form together with the nitrogen atom adjacent thereto an optionally substituted nitrogen-containing heterocycle; Y and Q are the same or different and each represents a bond or a spacer having 1 to 6 atoms in the main chain; --- represents a single or double bond; T1 and T2 represent each C(R9) (wherein R9 represents hydrogen, hydroxy, etc.), N, etc.; and Ar represents an optionally substituted aromatic group, hydrogen, etc., provided that a specific compound is excluded. |