| abstract |
Caspase-3 inhibiting compounds of formula (I): as well as pharmaceutical compositions and methods of treatment are disclosed. The compounds are useful for treating caspase-3 mediated diseases and conditions, among which are cardiac or cerebral ischemia or reperfusion injury, type I diabetes, immune deficiency syndrome, includings AIDS, cerebral and spinal cord trauma injury, organ damage during transplantation, alopecia, aging, Parkinson's disease, Alzheimer's disease, Down's syndrome, spinal muscular atrophy, multiple sclerosis and neurodegenerative disorders. |