| abstract |
A sustained release for comprising ce-lipoic acid or derivatives thereof is described and is characterized in that it consists of (a) at least one cationogenic polymer, (b) .alpha.-lipoic acid or derivatives thereof and (c) at least one acid different form (b). It has surprisingly been found in this connection that, besides controlled release of active ingredient over more than 8 hours and a prolonged GI transit time, there is also faster penetration of the ingredient. Completely unexpectedly, the sustained release form of the invention is additionally associated with an increased bioavailability of .alpha.-lipoic acid and derivatives thereof. |