http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2384439-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ebfd716a6d868cec0fdcf2af2480107 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 |
| filingDate | 2000-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4a0cf6e309a6053ef51463a938c2a30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2820ea139b3d8c7fdf64c986238bf1d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_569243c4e7731570dfb79f9df5837855 |
| publicationDate | 2001-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2384439-A1 |
| titleOfInvention | Modified adenoviral vectors for use in gene therapy |
| abstract | The present invention provides means and methods for the generation and manufacturing of recombinant Ad vectors that are modified in E2B and/or E4 functions, preferably, said vectors comprise E1 and/or E2A deletions. For th is purpose, the vector genome is modified in the respective promoter regions su ch that the promoter is only active in a suitable complementing cell line or on ly active following a certain signal in the case of an inducible promoter. The modified promoter is, on the other hand, inactive under normal conditions, a nd in normal mammalian and/or human cells. Hence, vectors that possess said modified promoter in the E2B and/or E4 region do not express the respective transcription region in mammalians and/or humans. |
| priorityDate | 1999-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 422.