| abstract |
A novel human dipeptidyl aminopeptidase (DPP8) with structural and functiona l similarities to DPPIV and fibroblast activation protein (FAP) has been identified and characterized. The novel peptide comprises the sequence ID NO : 1, the amino acid sequences His736GlyTrpSerTyrGlyGlyTyrLeu, Leu816AspGluAsnValHisPheAlaHis, Glu847ArgHisSerIleArg, Phe225ValLeuGlnGluGluPhe, or a sequence having at least 60 % homology with, and the substrate specificity of SEQ ID NO:1. A gene encoding the dipeptidyl peptidase and uses of the dipeptidyl peptidase. |