| abstract |
The invention relates to substituted indolinones of the general formula (I), in which R1 to R6 and X are defined as per claim 1, to their isomers and salts, in particular, their physiologically compatible salts which exhibit valuable pharmacological properties, in particular an inhibiting effect on various receptor tyrosine kinases, cyclin/CDK complexes and also on the proliferation of endothelial cells and different tumour cells. The invention also relates to medicaments containing these compounds, to their use and to a method for their production. |