abstract |
A polypeptide derivable from human NESP55 wherein the said polypeptide is derivable, or predicted from the amino acid sequence of human NESP55 to be derivable, by endoproteolytic cleavage of a polypeptide having the amino acid sequence (I) or (II) (human NESP55) or of a variant thereof, wherein the polypeptide variant has an amino acid sequence which has at least 90 % identity with the amino acid sequence given above. NESP55 or fragments thereof may be useful in medicine for the treatment of obesity. |