abstract |
Compounds represented by formulae (I) and (II) wherein each of Y, X and R individually is selected from the group consisting of hydrogen, hydroxy, hal o, CF3, NO2, CN, NH2, COR1 and CO2R2 wherein R1 is selected from the group consisting of alkyl, aryl, alkaryl, and NH2, and R2 is selected from the gro up consisting of alkyl, aryl and aralkyl, and provided that at least one of Y, X, and R is other than H; and pharmaceutically acceptable salts thereof are provided. Compounds of the formula are useful as analgesics for treating pai n, as immunomodulators and for treating drug abuse. |