Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_832999f230974e686160c11f3929678d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
filingDate |
2002-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb8ac1cfb0045bb5d5e33d41a51e2d93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49d736ce971899ffe76bb395ff23f9c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d217da269ca5e0c46024d9500ece49a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5dd2b11dd60908089cfb145ad2ec25b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ddbccf07bc7ab02c718e2d8be6ef60f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20238d8511a664bbbb8c959070a27c98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f562cb1da12367c500f37741298d08c |
publicationDate |
2002-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2378494-A1 |
titleOfInvention |
Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase, and materials and methods for identification of inhibitors thereof |
abstract |
The identification, isolation, purification, and characterization of the catalytic domain of the human hepatocyte growth factor receptor kinase (hHGFR) are described. A crystal structure of the hHGFR kinase domain is reported herein. This structure provides a three-dimensional description of the binding site of the hHGFR for structure-based design of small molecule inhibitors thereof as therapeutic agents. The kinase domain of human HGFR and its associated crystal structure is described for use in the discovery, identification and characeterization of modulators of human HGFR. |
priorityDate |
2001-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |