abstract |
The present invention relates to methods and materials for in vivo repair of cartilage (70) or bone (23) and cartilage defects in mammals. The invention relates to membranes (21, 50) carrying a composition comprising at least one stimulation molecule, which is capable of inducing signal transduction in chondroblasts/chondrocyt es and/or osteoblasts/osteocytes. Furthermore the invention relates to a method for the preparation of chondroblasts/chondrocytes (80) and/or osteoblasts/osteocytes suspensions (24). |