Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48de1cfdc993735cdc1c82f96827b33e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-66 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
2000-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87615400836c6245f15f9130108b1b63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32500add7d1db52fe463679a3a644cd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49f03c00f9eebd1bf1e89b0adba19833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6eecc98256aca5632cc5838aa6ccb41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9fd9f69566ea5436ac8f0c30cad6c18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f382986f20a79802fe705879052732c5 |
publicationDate |
2001-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2378016-A1 |
titleOfInvention |
Use of aspergillus sojae as host for recombinant protein production |
abstract |
A recombinant Aspergillus sojae comprising an introduced acetamidase S (amdS) gene as selectable marker is disclosed. An Aspergillus sojae exhibiting growth with medium comprising uracil and fluoro-orotic acid, said Aspergillus sojae further not exhibiting growth on medium comprising uridine and fluoro-orotic acid i.e. said Aspergillus sojae exhibiting uracil auxotrophy, said Aspergillus sojae being unable to utilize uridine, said Aspergillus sojae being pyrG negative, said Aspergillus sojae exhibiting resistance to fluoro-orotic acid, said uracil auxotrophy and said fluoro-orotic acid resistance being relievable upon complementation with an active introduced pyrG gene, is described. The Aspergillus sojae further comprises a nucleic acid sequence encoding a phytase or a protein having phytase activity or any other heterologous protein or polypeptide and can be used for the biotechnological production of said phytase or said other heterologous proteins or polypeptides. Additional mutants exhibiting amended morphology are also disclosed. Methods of producing such expression hosts are described. |
priorityDate |
1999-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |