http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2376860-C

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filingDate 2000-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2006-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a5e6a3653347238ddc9529aa9f693c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f005d074766870a39542264ddc202a75
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publicationDate 2006-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2376860-C
titleOfInvention Dinucleotide crystals
abstract The present invention is directed to crystals of P1-(2'- deoxycytidine 5'-)P4-(uridine 5'-)tetraphosphate (dCP4U) or a salt thereof and to a process for producing the crystals. The present invention also provides a process for producing dCP4U involving reacting uridine 5'-monophosphate (UMP), 2'- deoxycytidine 5'-monophosphate (dCMP), diphenyl phosphorochloridate (DPC), and pyrophosphate (PPi). The crystals of dCP4U obtained through the process according to the present invention have high purity and high stability and no hygroscopicity as compared with a freeze-dried product, and thereby serve as a useful raw material for preparing a pharmaceutical. The process for producing dCP4U according to the present invention permits use of inexpensive UMP as a raw material and realizes high yield. Thus, the process is suitable for large-scale synthesis of dCP4U.
priorityDate 1999-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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