| abstract |
Disclosed are methods for the identification of novel genes involved in a variety of cellular processes, including retinal degeneration, retinal disease, cancer, memory and learning, amylotropic lateral sclerosis, and methods for the identification of the function of a variety of genes and gene fragments of unknown function. Methods are also diclosed for making non-human animal models of diseases by in introduction of selected ribozymes to cleave target genes. The genes thus identified, as well as the compositions used in the identification methods, are also provided. |