| abstract |
This invention is directed to an (aminoiminomethyl or aminomethyl)benzoheteroaryl compound of formula (I): wherein X is O, S or NR 1 which is useful for inhibiting the activity of Factor Xa by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of formula (I), methods f or their preparation, their use, such as in inhibiting the formation of thrombi n or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.</SD OAB> |