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filingDate 2001-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2002-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2356024-A1
titleOfInvention Process for the production of human cartilage implants by means of chondrocytes cultivated in vitro
abstract The invention describes a process for the production of a human cartilage implant from chondrocytes cultured in vitro, which come as close as possible to the original with respect to their biochemical composition and biomechanical properties. Up to 20% by vol. of human serum are used as medium addition in the process. The chondrocytes can be kept in monolayer culture until the 12th passage in order firstly to be re-differentiated under a reduced oxygen partial pressure and subsequently to be stimulated to form a three-dimensional cartilage tissue due to aggregation under an oxygen partial pressure of 21%.
priorityDate 2000-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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