http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2355696-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6919 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1274 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate | 1999-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_432ad4dfdf5b13a9c60a0c88a53f7455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dca04d76bafc126592377e8f9cb4e037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11947218c3f57a71009278648885534a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da7ddd3b38cfd899480d10914905a3c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cd67c392c4bc79832e4f9958050d34a |
| publicationDate | 2000-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2355696-A1 |
| titleOfInvention | Therapeutic delivery using compounds self-assembled into high axial ratio microstructures |
| abstract | Therapeutic complexes comprising plural therapeutic compounds self assembled into high axial ratio microstructures are described. The therapeutic complexes satisfy the formula HARM-Th, wherein HARM is a high axial ratio forming material and Th is a therapeutic coupled to or associated with the HARM. The therapeutic complexes also can satisfy the formula HARM- S- Th, wherein S is a spacer. Release of the therapeutic by the complex generally follows either 0-order kinetics or pseudo-first order kinetics. A method for delivering therapeutics to organisms, particularly humans, also is described. The method comprises administering an effective amount of (1) a ligand, such as a therapeutic, self-assembled into a HAR microstructure, or (2) a ligand, such as a therapeutic, coupled to or associated with a material capable of thereafter self-assembling into a high axial ratio microstructure, to the mammal. Nucleic acids are an example of a ligand that can be administered effectively according to this method through noncovalent attachment to the HARM-forming materials. |
| priorityDate | 1998-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 628.