http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2355138-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eccd894c99fea2d1c0c8735872bb2309 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-10 |
| filingDate | 1999-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5e2242fb47a313efa1ca5e3aa5a0d97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dc10c7fd7ddad3493ae433c5bbfc0b0 |
| publicationDate | 2009-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2355138-C |
| titleOfInvention | Process for the preparation of 3-alkanoyl- and 3-alkylindoles |
| abstract | Process for the preparation of compounds of the formula I (see formula I) in which R, R1, R2 and n are as defined in Claim 1, and X is O or H,H and their acid addition salts, characterized in that a) if X is O and R, R1, R2 and n are as defined above, a compound of the formula II (see formula II) in which R1 and R2 are as defined in Claim 1 is reacted with a compound of the formula III R-(CH2)n-CO-L III in which R, L and n are as defined in Claim 1 in a Friedel-Crafts acylation with catalysis of Lewis acid metal halides of the type R'-Al(Cl)2, in which R' is as defined in Claim 1, or b) if X is H,H and R, R1, R2 and n are as defined above, a compound of the formula I in which X is O and R, R1, R2 and n are as defined above, is reduced using complex hydrides with activation by Lewis acid metal halides of the type R'-Al(Cl)2, in which R' is as defined in Claim 1, and/or in that a resulting base of the formula I is converted into one of its acid addition salts by treatment with an acid. |
| priorityDate | 1998-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.