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filingDate 1999-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6930e548e4e28d211c25b16d9472487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f617a9d27ed7d4764372dcfdbfe352a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_680b4963d84cf21bee97b24c70f30a15
publicationDate 2000-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2354451-A1
titleOfInvention Halovir, an antiviral marine natural product, and derivatives thereof
abstract The present invention provides a compound having the structure (I) wherein Rla and R1b are independently selected from the group consisting of -H, alkyl, lower-alkyl, substituted alkyl and substituted lower-alkyl; R2a and R2b are independently selected from the group consisting of -H, lower-alkyl, and substituted lower-alkyl; R3 is -H, lower-alkyl, substituted lower-alkyl and where R3 and R4 are attached together by a lower-alkyl or a substituted lower-alkyl moiety; R4 is -H, lower-alkyl, substituted lower-alkyl and where R3 and R4 are attached together form a lower-alkyl or substituted lower-alkyl bridge; R5, R7, R9 and R11 are independently selected from the group consisting of -H, lower-alkyl, and substituted lower-alkyl; R6 is -H, lower-alkyl and substituted lower-alkyl; R8 is -H, lower-alkyl and substituted lower-alkyl; R10 is -H, lower-alkyl and substituted lower-alkyl; R12 is -H, lower-alkyl and substituted lower-alkyl; and A is -C(O)-R13, wherein R13 is -H, -OH, alkyl, lower-alkyl, substituted lower-alkyl or -O(lower-alkyl); -CH2-OR14 wherein R14 is -H, -C(O)CH3, alkyl, lower-alkyl or substituted lower-alkyl; or -CH2-NR15R16, where R15 and R16 are independently selected from -H, lower-alkyl, alkyl, substituted lower-alkyl or substituted alkyl; a pharmaceutically acceptable salt or derivatives thereof, useful for preventing or treating viral and microbial infections.
priorityDate 1998-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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