Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2de1389433aab193063aa0a2c8c693d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-334 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6408 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-07 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11D3-386 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 |
filingDate |
1999-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af69d6786ed3b26c80cdc909e8ec7f11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c692310a54a9137dffe1879cc93604e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c86e19133c6f8100babfd8ab1eb4ed87 |
publicationDate |
2012-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2353789-C |
titleOfInvention |
Chemically modified enzymes with multiple charged variants |
abstract |
This invention provides modified enzymes comprising one or more amino acid residues replaced by cysteine residues, where the cysteine residues are modified by replacing the thiol hydrogen in the cysteine residues with a substituent group providing a thiol side chain comprising a multiply charged moiety. The enzymes show improved interaction and/or specificity and/or activity with charged substrates. |
priorityDate |
1998-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |