http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2353375-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_046e16bd6918ef3cd62184605b15a413 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-39 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-24 |
| filingDate | 2001-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16f685bcf503607aeac057f2ae22fbe9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf89e2bf52677b18b9f03e8139a4f199 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87f444e1483a4064e9d52683c03ba5c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62a7179752e6a2e0d5eed8c5c4c91e4c |
| publicationDate | 2007-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2353375-C |
| titleOfInvention | Process for producing optically active alcohol |
| abstract | A novel process in which an optically active alcohol compound having a desired absolute configuration and a high optical purity can be obtained by asymmetrically hydrogenating a .beta.-keto acid compound through a simple operation. An optically active alcohol represented by the following general formula (III) : (see formula III) (wherein R1 represents a C1-C15 alkyl group which may have one or more substituents (selected from halogen atoms, a hydroxyl group, an amino group, amino groups protected by a protective group, amino groups protected by a mineral acid or organic acid, amino groups substituted with one or more C1-C4 lower alkyl groups, a benzyloxy group, C1-C4 lower alkoxy groups, C1-C4 lower alkoxycarbonyl groups, and aryl groups) or an aryl group; and R2 represents a C1-C8 lower alkyl group, or a benzyl group which may have one or more substituents) is obtained by asymmetrically hydrogenating a .beta.-keto ester compound represented by the following general formula (I) : (see formula I) (wherein R1 and R2 are the same as defined above) in the presence of at least one ruthenium complex having as a ligand an optically active tertiary diphosphine compound represented by the following general formula (II): (see formula II) (wherein R3 and R4 each independently represent a cycloalkyl group, an unsubstituted or substituted phenyl group, or a five-membered heteroaromatic ring residue). |
| priorityDate | 2000-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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