| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_905e8de029e16a0e19189751d9a5a6a1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate |
1999-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32ec3a749520b21283e4e850a015f00b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ecde56022911794e5225a36c6758433
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97b30627e18b859ef9fae8fc826b16ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f8cf9914fc0436f25b3f3598e8aa128
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_598696af922c4a922bfc4ef1456dce80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e6c3c731815e5648ac42e4b6d3b2379 |
| publicationDate |
2000-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2352162-A1 |
| titleOfInvention |
Novel intermediates, process for preparing macrolide antibiotic agent therefrom |
| abstract |
The present invention provides a process for preparing a high yield of purified clarithromycin having broad antimicrobial activity as a macrolide antibiotic agent by using 1,3-benzodithiol-2-ylium tetrafluoroborate (BDFT), which can easily be synthesized from anthranilic acid and used as a protecting group for oxime. In addition, the present invention also provides a process for preparing clarithromycin from 1,3-benzodithiol-2-sulfonic acid group that forms clarithromycin salt which precipitates into crystals in reaction solution thereof, and purifying clarithromycin including a significantly simplified purification step. |
| priorityDate |
1998-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |