| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fc0668fd5cbfe23cea7d9bdd5de932a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-54 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G2-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 |
| filingDate |
1999-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c37aeb2f3b501690744804a242ee3185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f353f08221b286477dfdbe5b5f0290b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49de2500755cd3531ba4f2e614222387
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70d966f0e2274acc410e00e1e97ab692
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_002a2928cc522b1b70eb41b33c9910d5 |
| publicationDate |
2000-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2345934-A1 |
| titleOfInvention |
Coupled peptides |
| abstract |
The present invention is directed to a process for coupling an adhesive glycoprotein to a surface of a bulk material comprising the following steps: a) a layer of a volatile aldehyde is deposited to the surface of the bulk material from a gas plasma atmosphere, b) the layer so formed on the bulk material is contacted with a cell-adhesive glycoprotein having amino groups, c) the coupling of the amino groups of the glycoprotein to the carbonyl grou ps of the deposited aldehyde layer is strenghthened by transforming the primari ly formed -CH=N- bonds in the presence of a reducing agent into -CH2-NH-bonds; and to a cell growth material comprising a bulk material having at least one surface to which a cell adhesive glycoprotein having amino groups is coupled characterized in that said amino groups are covalently bonded to aldehyde groups of a layer of a volatile aldehyde, deposited to the surface of said bulk material from a gas plasma atmosphere, via first formed -CH=N- groups which have been transformed into -CH2-NH- groups in the presence of a reduci ng agent. |
| priorityDate |
1998-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |