Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_acae5cf784b925a541386e9c5bc9e00a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-543 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate |
1999-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9727b05a5022f8ff20f45764318e1d23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f81afc984b76650888b374598899c335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a8e4b19bc7f97375ce176d897aec642 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_895496f9e38a7b15da7281bd1db2bb2e |
publicationDate |
2000-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2345532-A1 |
titleOfInvention |
Delivery of phosphoinositide polyphosphates into cells |
abstract |
A method for facilitating delivery of a phosphatidylinositol polyphosphate o r derivative thereof into a eukaryotic cell is disclosed. The method includes forming a complex of the phosphatidylinositol polyphosphate or derivative wi th a polyamine, and then contacting the cell with the complex. Preferred polyamines include aminoglycosides, dendrimeric polyamines, and histones. Compositions of matter for use in the method are also described. A method fo r screening compounds for minimum toxicity to eukaryotic cells and maximum toxicity to bacterial cells is also disclosed. Also disclosed is a method fo r monitoring calcium flux in a cell. |
priorityDate |
1998-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |