http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2344618-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d2eb3a8fc6394e5eb29ccf10e48e05a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 1999-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3954e1feb897f380053922b5e7ef45d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0995a2bb24488f737067026522be1ca9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d959492e0158257b2d970a3f4855b8ed |
| publicationDate | 2000-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2344618-A1 |
| titleOfInvention | Method for identifying compounds affecting rna/rna binding protein interactions |
| abstract | Disclosed are nucleic acid sequences which, when present in an RNA molecule, bind to RNA binding proteins. These nucleic acid sequences are present in untranslated regions of certain mRNA. They can be used in assays to identify compounds that affect the interaction of RNA containing the nucleic acid sequence, such as the source mRNA, and RNA binding proteins. The disclosed nucleic acid sequences can also be used to identify RNA binding proteins tha t can interact with the sequences. An assay for identifying compounds that affect interaction of RNA containing one of the disclosed nucleic acid sequences and RNA binding proteins is also disclosed. The assay involves detecting interactions between RNA binding proteins and an RNA molecule containing one of the disclosed nucleic acid sequences in the presence of a test compound and in the absence of the test compound. A difference in the detected interaction in the presence and absence of the test compound indicates that the compound affects the interaction. The identified compound s can be used to affect the interaction of RNA binding proteins with mRNA containing the nucleic acid sequences or related sequences. |
| priorityDate | 1998-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.