| abstract |
The invention relates to novel compounds of formula (I): (see formula I) wherein n represents an integer from 0 to 6; R1 represents a atom hydrogen, a hydroxy, cyano, alkoxy, alkoxycarbonyl, carboxy or aminocarbonyl, or a group of formula NR4R5 in which R4 and R5, identical or different, represent an alkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl, cycloalkylalkyl, alkenyl or alkynyl; R2 represent represents a hydrogen atom, an alkyl or hydroxymethyl group, or a group of formula (see formula II) and -UVW in which T represents a group cycloalkyl, U represents a bond or a methylene group, V represents a bond, an oxygen atom or a group S (O) q in which q is an integer understood between 0 and 2 inclusive, and W represents an aryl, arylalkyl group, cycloalkyl or cycloalkylalkyl; and R3 represents a hydrogen atom or a group alkyl, aryl or heteroaryl. The invention also relates to the isomers of the compounds of formula (I) as well that their addition salts with an acid or a pharmaceutically acceptable base acceptable. The compounds according to the invention are useful as medicaments for Treatment of anxiety, panic attacks, obsessive-compulsive disorder, phobias, impulsive disorders, drug abuse, cognitive disorders, psychoses, depressions and mood disorders. |