Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate |
1999-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93df1020142c5ba32a2ce1fc77afb0ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b281e025c5aae6bceb0a2a5c9a4f73c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_512a87b4dcff5b5e8d4710fd32f5634d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd1a908ed5f8103024c15bfb2f1f35d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_135bed89963fd7a630fbbbfa2e364cf2 |
publicationDate |
2000-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2341650-A1 |
titleOfInvention |
Carbapenem antibacterial compositions and methods of treatment |
abstract |
The present invention relates to novel 2-(naphthosultamyl)methyl-carbapenem antibacterial agents or pharmaceutically acceptable salts thereof in combination with other .beta.-lactams, which are useful in treating and preventing enterococcal infections. The combinations have anti-PBP5 activity as well as activity against the critical PBPs of sensitive isolates. The antibacterial compositions of the present invention thus comprise an importa nt contribution to therapy for treating infections caused by these difficult to control pathogens. This combination is also useful against gram positive microorganisms, especially methicillin resistant Staphylococcus aureus (MRSA ), methicillin resistant Staphylococcus epidermidis (MRSE), and methicillin resistant coagulase negative Staphylococci (MRCNS). |
priorityDate |
1998-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |