abstract |
The invention relates to water soluble antitumor analogs of paclitaxel of formula (I) wherein R1 = C(O)CH2CH(OH)COOX, R2 = H, C(O)CH2CH(OH)COOX, X = H, Li, Na or any other pharmaceutically acceptable counterion, as well as to a pharmaceutical composition comprising an antineoplastically effective amount of such analogs as an active ingredient. |