abstract |
Novel IRAP-BP polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length IRAP-BP polypeptides, the invention further provides isolated IRAP-BP fusion proteins, antigenic peptides and anti-IRAP-BP antibodies. The invention also provides IRAP-BP nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an IRAP-BP ge ne has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided. |