Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdaa64756184e715af6cb25ebc318917 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-806 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6842 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-11 |
filingDate |
1999-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_281e227492b0281cfe492b1a01a3014b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_239db1940cfc3cbead6218759c9b7b0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33c6a415554b286cfa88e8dc090cebe0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cd45ec89660c5488ce76ccc4b2f5287 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_943047d2b422bb55aa48d439cd29b3a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65b89ccfdb9361c5399869c16109152a |
publicationDate |
2016-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2337688-C |
titleOfInvention |
Treatment of autoimmune conditions with copolymer 1 and related copolymers |
abstract |
The present invention is directed to polypeptides and peptides containing at least three amino acids randomly joined in a linear array; wherein at least one of the three amino acids is an aromatic amino acid, at least one of the three amino acids is a charged amino acid and at least one amino acid is an aliphatic amino acid. In a preferred embodiment the polypeptide contains three or four of the following amino acids: tyrosine, alanine, glutamic acid or lysine. According to the present invention, the present polypeptides bind to antigen presenting cells, purified human lymphocyte antigens (HLA) and/or Copolymer 1-specific T cells. Morever, according to the present invention, these polypeptides can be formulated into pharmaceutical compositions for treating autoimmune disease. The present invention further contemplates methods of treating an autoimmune disease in a mammal by administering a pharmaceutically effective amount of any one of the present polypeptides or peptides to the mammal. |
priorityDate |
1998-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |