| abstract |
The present invention relates to novel 2.5-substituted benzol sulfonyl ureas and thio ureas of formula (I). wherein R(1), R(2), R(3), R(4). X and Y have the meanings cited in the claims. The inventive compounds are useful active ingredients for medicaments The compounds of formula (I) act as inhibitors on ATP-sensitive potassium canals and are suitable for the treatment of cardio-vascular disorders, especially the treatment of arrhythmias, preventi on of sudden death from heart disease or affect diminished contractility of the heart. The invention also relates to methods for producing compounds of formula (I), the use thereof and pharmaceutical preparations containing said compounds. |