Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4289a396c910b8d5e3224d77e9ebe404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba8bdab7ff67ed3f60e2933e9c4be6f3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4707 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4716 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
1999-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2007-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_995b2efc26e6a9a2d524865375a8ddc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16747fb24a0523323ba8a807d90ffb07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c357ba1d4d827b88079c430c5ce08bc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f0e1c4b5595d0886e63c86168fe9760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4710633161532ddafa761aff328790a5 |
publicationDate |
2007-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2333469-C |
titleOfInvention |
Myotilin, an actin-organizing protein |
abstract |
The present invention concerns a novel cytoskeletal protein, myotilin, which contains Ig-like domains homologous to a giant sarcomeric structural protein titin. Myotilin is expressed in skeletal and cardiac muscles, it colocalizes with .alpha.-actinin in the sarcomeric I-bands and directly interacts with .alpha.-actinin. Expression of myotilin in mammalian non-muscle cells and in yeast causes reorganization of actin into thick F-actin bundles and inhibits growth of yeast cells.</SDO AB> |
priorityDate |
1998-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |