| abstract |
Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having structure (I) or (II), wherein Y1 and Y2 are independently selected from the group consisting of hydrogen, C1-4 alkyl, C1-4 alkoxy, C3-7 cycloalkyl, halogen, and trifluoromethyl; and A is (III), (IV), (V), or (VI). |