Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8271089d38632dcfdda0d75077c97c8c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1623 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J2-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
filingDate |
1999-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_141b0e5612b19562a2aad2c6f7b6b21b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7fdde2e1803d48e598b5fd2134e3539 |
publicationDate |
1999-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2323062-A1 |
titleOfInvention |
Colonic delivery of protein or peptide compositions |
abstract |
A method for delivering an active protein (preferably an immunoglobulin) or a peptide to the colon and a coated multiparticulate dosage composition for orally delivering an active protein or peptide to the colon produced by the method comprising: a) providing an aqueous PEG solution; b) providing a dry, homogeneous mixture of the active protein or peptide and microcrystalline cellulose; c) spraying said aqueous PEG solution onto said homogeneous mixture; d) extruding; e) spheronizing the extrudate; f) drying; g) screening the dried composition to form multiparticulates; h) collecting and subsequently coating said multiparticulates. |
priorityDate |
1998-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |