abstract |
A pyridine derivative represented by formula (1) [wherein R represents a halogen atom or a halogen-substituted lower alkyl; R2 and R3 respectively represent a hydrogen atom or a halogen atom; V represents a group: -C(=O)NH-, -NHC(=O) or NH-; and A represents A1, A2 or A3: (groups in A1 to A3 respectively represent a hydrogen atom, a lower alkyl, a lower alkanoyl, hydroxyl, benzoyl or an oxo group)] or a pharmaceutically acceptable salt thereof. The compound (1) inhibits collagen production and is useful for preventing or treating fibrosis. |