Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59ee7410b0c32079728a23dd93c7da02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 |
filingDate |
1998-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2010-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84a26a970c3c71a956e9228819ffd2d6 |
publicationDate |
2010-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2309326-C |
titleOfInvention |
Pharmaceutical compositions containing cyclodextrins and taxoids |
abstract |
A process for the preparation of rapidly soluble products for pharmaceutical use is provided. The process comprises the following steps: dissolving in ethanol a taxoid or a salt, or a hydrate, or a solvate thereof; adding to the solution a lyophilized solid cyclodextrin derivative; and evaporating the solvent and drying to obtain a solid, which comprises the taxoid as the active ingredient and the cyclodextrin derivative. The weight ratio of taxoid:cyclodextrin derivative ranges between 1:25 and 1:400. The taxoid is selected from the group consisting of paclitaxel and docetaxel, and the cyclodextrin derivative is selected from the group consisting of acetyl-y-cyclodextrin and hydroxy-propyl-.beta.-cyclodextrin. When hydroxy-propyl-p-cyclodextrin is used, the taxoid can be only docetaxel in a 1:25 to 1:100 taxoid:cyclodextrin weight ratio. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11406595-B2 |
priorityDate |
1997-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |