| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-16 |
| filingDate |
1998-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e2462b245c167cdcac1b99109d39394
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36e96a1a0656fd4ba6a922f32729c868 |
| publicationDate |
2013-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2308571-C |
| titleOfInvention |
Single-chain bifunctional glycoprotein hormones |
| abstract |
Single-chain agonists and/or antagonists of the glycoprotein hormones are disclosed. These proteins are of the formulae: (1) .beta.1-(linker1)m-.alpha.-(linker2)n-.beta.2; or (2) .beta.1-(linker1)m-.beta.2-(linker2)n-.alpha.; or (3) .alpha.-(linker1)m-.beta.1-(linker2)n-.beta.2, wherein each of .beta.1 and .beta.2 has the amino acid sequence of the .beta. subunit of a vertebrate glycoprotein hormone or a variant thereof; ".alpha." designates the .alpha. subunit of a vertebrate glycoprotein hormone or a variant thereof; "linker" refers to a covalently linked moiety that the spaces .beta.1 and .beta.2 subunits at distances from the .alpha. subunit and from each other effective to retain said activity, and each of m and n is independently 0 or 1. |
| priorityDate |
1997-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |