| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2de1389433aab193063aa0a2c8c693d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-86 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D11-0017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D11-0023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23G4-123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23K20-189
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-3945
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-3907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-38609
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-386
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-38618
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-38681
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-66 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-07 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23G4-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23G4-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K1-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q11-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11D3-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11D3-386
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11D7-42 |
| filingDate |
1998-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_075fe1b9f8c8adc06f836190ff184be8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ae56297c4c108b281fa25e100e9c195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6eb206a390bc4f00d78fba9059dfec81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6e036180f93b790425f463d32495585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04f92dd9db72d7287056292554d431c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0138965d95b5b96198a9d73a4cb22734
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdf0888e5e23dd450c59729c4bd8c346
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0dcb0b7cfd9821f29faab207c787f71 |
| publicationDate |
2011-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2308113-C |
| titleOfInvention |
Multiply-substituted protease variants with altered net charge for use in detergents |
| abstract |
Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Protease variants are provided that contain substitutions of the amino acids at one or more residue positions so that the substitution alters the charge at that position to make the charge more negative or less positive compared to a precursor protease and thus the protease variant is more effective in a low detergent concentration system than a precursor protease. Also provided are protease variants containing substitutions of the amino acids at one or more residue positions so that the substitution alters the charge at that position to make the charge more positive or less negative compared to a precursor protease and thus the protease variant is more effective in a high detergent concentration system than a precursor protease. |
| priorityDate |
1997-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |