Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_963a5cc60c3fa17af8b5be89eddaec17 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14152 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
filingDate |
1998-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97d4d39d016e1eacaf0cf48ae181434e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d36545da7731ec7b1cedf6d9819aee8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ee33f98446211db67b95fc6cb9938dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96ca755a3eccef63dba2b1b28a4111d6 |
publicationDate |
1999-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2308008-A1 |
titleOfInvention |
Amplifiable adeno-associated virus (aav) packaging cassettes for the production of recombinant aav vectors |
abstract |
High-efficiency AAV packaging constructs and methods for their use are provided in the present invention. These high-efficiency packaging constructs comprise an activating element (such as the P1 sequence located within the AAV S1 integration site of human chromosome 19) amplifiably linked to one or more AAV packaging genes. The constructs may be either integrated into a mammalian cell genome or maintained episomally. Use of the high-efficiency AAV packaging vectors of the invention provides for controlled amplifiable production of rAAV vector constructs. |
priorityDate |
1997-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |