http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2306741-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ddb9f3656270bc5410be3679322fead |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-29 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-36 |
| filingDate | 1999-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_183b443c718f7cc97dde3a9596cad20f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d25ba8f5a3cc28f95825823a755fad05 |
| publicationDate | 2000-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2306741-A1 |
| titleOfInvention | Process for the preparation of (2r, 3s)-3-amino-1,2-oxirane |
| abstract | A process for the preparation of (2R, 3S)-3-amino-4-phenylbutane-1,2-epoxide, which comprises treating a (2S, 3S)-3-amino-1-halo-2-hydroxy-4-phenylbutane or (2S, 3S)-3-amino-4-phenylbutane-1,2-epoxide either with a quaternary ammonium carboxylate or with both a metal carboxylate and a quaternary ammonium salt to prepare a (2S, 3S)-1-acyloxy-3-amino-2-hydroxy-4-phenylbutane, treating this compound with a sulfonyl halide in the presence of an organic base to prepare a (2S, 3S)-1-acyloxy-3-amino-2-sulfonyloxy-4-phenylbutane, and subjecting the compound thus obtained to treatment with an inorganic base. This process makes it possible to efficiently produce intermediates for HIV protease inhibitors by using L-phenylalanine as a raw material. |
| priorityDate | 1998-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.