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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-36
filingDate 2000-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10f9a04e4e646570e8e1862ae9bdf287
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4904ec70e30f3cf10af742a67013b5fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e3c0642915fa547fa67770613a8453f
publicationDate 2000-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2300792-A1
titleOfInvention An agent for increasing chemokine production
abstract The present invention is to offer am agent for increasing chemokine production which is useful for the treatment of AIDS. The effective component of the agent of the present invention for increasing chemokine production is an extract from inflammatory tissue inoculated with vaccinia virus. The extracts from inflammatory tissue inoculated with vaccinia virus increase the production of chemokines such as MIP-1.alpha., MIP-1.beta. and RANTES which are HIV-suppressive factors released from CD8+T cells. The extracts also have suppressive effects on SIV infection and on SIV replication. Therefore, the agent of the present invention containing such extract is useful as an anti-HIV drug with new mechanism of action different from those of known therapeutic agents for AIDS, such as reverse transcriptase inhibitors and protease inhibitors. The agent of this invention is very useful as a new drug for the treatment of AIDS with high safety.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102791277-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102791277-B
priorityDate 1999-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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