abstract |
Disclosed is a novel process and novel intermediates to prepare [R-(R*,R*) ]-N-L3-[1-[5, 6-dihydro-4-hydroxy -2-oxo-6-(2-phenylethyl) -6-propyl-2H-pyran-3-yl]propyl]phenyl]-5- (trifluo-romethyl)-2- pyridinesulfonamide (XIX) which is a protease inhibitor useful in treating humans infected with the HIV virus. |